Prepare Coating Station: In a large bowl, combine flour, garlic powder, onion powder, salt, and black pepper. In a separate bowl, whisk eggs and milk. Then place the breadcrumbs in a third bowl.

Heat Oil: Pour enough vegetable oil into a frying pan to cover the bottom by about 1/2 inch. Heat over medium-high heat until it shimmers.

Coat Mushrooms: Slice fresh mushrooms. Dredge each slice in the flour mixture, then dip in the egg mixture, and finally press into the breadcrumbs.

Fry Mushrooms: Carefully add the coated mushroom slices to the hot oil. Fry for 2-3 minutes on one side until golden brown, then turn and fry for another 2-3 minutes.

Crisp Up: Remove mushrooms using a slotted spoon and place on paper towels to drain excess oil.

Serve: Transfer fried mushrooms to a serving platter and serve immediately with ranch dressing.